#5 Shrink-Ray (Duke Nukem 3D) - [ PC ]
This innovative weapon titillated gamers way back in 1996, and it's not hard to see why. What other gun lets you shrink opponents down to rodent-size, only to be squashed under your mighty boot? Talk about cutting an enemy down to size. But there's one key defense: you can counteract the effects by gulping a bottle of steroids. Hey, The Duke isn't exactly known for his subtlety.