If you haven't run into any of the baddies on this list, consider yourself lucky.
Some enemies on this list are incredibly difficult, while others look ugly or make obnoxious noises. But Half-Life's Barnacle is an exception: it's annoying simply because it's there. Stuck to the ceiling, it's hardly a serious threat. If you're stupid enough to stumble into that huge tongue, you deserve to have your head bitten off.
These chainsaw-wielding freaks in Resident Evil 4 can absorb a sickening amount of punishment. What's worse, one whack from that chainsaw will chop off your head--one-hit kills suck! But as bad as these chainsaw maniacs are in the single-player mode, they become almost unstoppable in the Mercenaries mini-game. Dr. Salvador, for instance, is able to jump several stories high to reach you. Keep running!
Heavy Armors are immune to hand-to-hand combat and can guzzle down bullets like so much popcorn. If you want to take down one of these guys, try using the 20mm Repeating Cannon or the Multi-Rocket Launcher. In a pinch, about a half million grenades will do the job. Just watch out for their wicked nail guns!
These pipsqueaks are among the most obnoxious virtual adversaries ever conceived. Grunts aren't exactly difficult, but their high-pitched shrieking and cowardly combat tactics make them enormously distracting when you're facing down the infinitely tougher Elites. Don't bother wasting bullets--just club these fools out of your way.
Remember this jerk? He'd rudely slurp the life right out of you, and was totally immune to any and all physical attacks. Luckily, a strong dose of magic could melt his face like so much Gorgonzola cheese. Death quesadillas, anyone? "Wizard needs food badly!"
